Re: [DIYbio] automatic planning for molecular cloning workflows?

On Thu, Mar 15, 2012 at 9:18 PM, Patrick O'Neill
<synapse.and.syntax@gmail.com> wrote:
> The topic of scientific robots is a popular one on this list, but I'm
> more interested in the issue of workflow planning: can you take a
> natural language command like "amplify insulin" and translate that
> automatically into a detailed protocol?

you might be interested in reading some stuff from the archives:
http://groups.google.com/group/diybio/browse_thread/thread/19df187ef1014735
http://news.ycombinator.com/item?id=2191105
http://88proof.com/synthetic_biology/blog/archives/290
http://groups.google.com/group/openmanufacturing/browse_frm/thread/a8d8ee245aaae97d#
http://groups.google.com/group/openmanufacturing/browse_frm/thread/b2e21ccc953d6328#

The language technology is easy. What I would like is to then
automatically generate a microfluidic lab on a chip that implements
the protocol, or generate beautiful documentation for the workflow
that I could give to a team of people (or, er, just myself). But most
people just use gradstudents, yes...

> It sounds like an impossible problem, but there appears to have been

doesn't sound impossible

> What ever happened to this stuff?  The first generation of programs
> was hampered by the problem of large knowledge-bases, which restricted
> them to trivial experiments.  But dealing with large knowledge-bases
> is a problem we've gotten a little better at in the last thirty years.

problems with knowledge-based stuff:
1) figuring out a good format/represetation
2) collecting it without killing ourselves in the process
3) finding something useful to do with it (sometimes this can pay for
the other two steps)

>  Is anyone familiar with more recent efforts at this problem?  Does
> anyone use anything that sounds vaguely like what I described?

biocoder ain't it

- Bryan
http://heybryan.org/
1 512 203 0507
irc.freenode.net ##hplusroadmap

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