http://www.worthington-biochem.com/pap/default.html
That website says it's pretty thermostable (up to 60 to 70C )and most active from 6-7 pH
http://en.wikipedia.org/wiki/Papain also states its use in cell culture to digest extra-cellular matrix in just 5-10 minutes, and gives the citation [7]
Sounds like it's as simple as "just add water", although for a starting concentration I'd have no idea.
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