Re: [DIYbio] Re: Meeting times

I'm concerned about security of the DNA sequence (not being modified
in transit) whether it's *digital* or *physical*. RFLP could be a good
*physical* DNA hash, Bryan are you saying a checksum of a *digital*
DNA .txt file is sufficient for digital verification?

That 'Cloud Culture' includes the word 'Culture' that seems to mean
live/stable bugs or physical DNA is involved in storage and transit. I
do not think the infrastructure is present yet to support that... ok
there are fridges, but the only DIY suspension culture stuff I've
seen was on E.coli agar stabs. What about the 10s of other strains we
could rattle off a list of that would be cool to have on hand?
Replicating thousands of *physical* parts and distributing them to
multiple peers just seems way too much to do right now... at least
compared to keeping the DNA in *digital* form now.

I expect *digital* DNA to *physical* DNA converters' prices will come
down in the next 2-4 years, I can wait that long.

On Mon, Oct 1, 2012 at 6:05 PM, Cathal Garvey <cathalgarvey@gmail.com> wrote:
> Key signing and hash verification etc. are all well and good, but they
> don't mean anything until you can verify that the hashed-and-signed
> digital representation actually matches the DNA.
>
> To meaningfully confirm the content of a DNA strand calls for a DNA
> hashing method; DNA barcoding is a step in this direction for whole
> species, but a method for smaller molecules that generates useful and
> visibly distinct output would be needed to "hash" plasmids.
>
> On 01/10/12 22:57, Bryan Bishop wrote:
>> On Mon, Oct 1, 2012 at 4:51 PM, Nathan McCorkle <nmz787@gmail.com> wrote:
>>
>>> I would actually worry more about physical DNA being faked or 'malwared',
>>> so I'm a propenent of keeping the repo digital. We should start by
>>> mirroring the existing registry(s).
>>
>>
>> I am surprised Marc hasn't setup public key signing of the DNA samples from
>> Biofab yet. Hmm. This is a probably a thing that we should do.
>>
>> - Bryan
>> http://heybryan.org/
>> 1 512 203 0507
>>
>
> --
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--
Nathan McCorkle
Rochester Institute of Technology
College of Science, Biotechnology/Bioinformatics

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