The research studies in the paper likely cost a few thousand dollars or less in supplies, and took a year or two of work in the lab. So it could be replicated in a DIYbio lab. Or someone could try a variation on the experiments described in the paper.
In terms of equipment, it requires being set up for basic molecular biology--PCR, gel electrophoresis, autoclave, balance, a few water baths and dry incubators. The only special equipement would be a microscope set up for yeast tetrad dissection. The lab strains of yeast are available, and gene knockout in yeast is easier than in any other organism.
Jim Lund
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