Oligo synthesis is Very Old technology where there was a big drop in price that corresponded to the end of the Carruthers patent. Today, the cost and thus price for traditional oligo synthesis is very stable and not likely to change because the raw materials vendors and oligo houses are surviving with very little, if any, profit.
But, there are a couple of new companies such as Cambrian Genomics in San Francisco that are employing new technology to allow them to reduce the costs of oligo synthesis by orders of magnitude. If companies like Cambrian are successful (co founded by Church) you will likely see a dramatic drop in the cost of synthetic, I've been told dow to a few cents per base pair.
Please check out this company...
Azco Biotech, Inc.
3626 Ocean Ranch Blvd.
Oceanside, CA 92056
t. 858-525-2770
-------- Original message --------
From: Patrik D'haeseleer <patrikd@gmail.com>
Date: 03/11/2013 3:24 PM (GMT-08:00)
To: diybio@googlegroups.com
Cc: Patrik D'haeseleer <patrikd@gmail.com>,Bryan Bishop <kanzure@gmail.com>
Subject: Re: [DIYbio] Re: DIY DNA synthesis?
Do you have any current data along these lines? I'm going by some graphs I've seen George Church and others present a while back, but I've seen precious little new data. Even in DNA sequencing, most of the graphs I keep seeing tends to be a couple of years old by now ($1000 genome by end of 2012 - really?)
I'd love to some data that's a little less stale by now - especially for a field that is developing this rapidly.
Patrik
On Monday, March 11, 2013 3:03:19 PM UTC-7, Bryan Bishop wrote:
On Mon, Mar 11, 2013 at 5:01 PM, Patrik D'haeseleer <pat...@gmail.com> wrote:--
> One important thing to keep in mind that oligo synthesis is really getting
> commoditized. It's definitely not as cheap as sequencing, but it seems to be
> growing on a similar exponential trend - just a couple years behind
> sequencing.
The graphs/trends don't seem to support that. Oligonucleotide
synthesis has been more or less at the same place for a few years now.
Also, assembly time is all over the map (weeks - months) for longer
sequences.
- Bryan
http://heybryan.org/
1 512 203 0507
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