On Wednesday, July 24, 2013 2:10:01 PM UTC-4, Nathan McCorkle wrote:
What's a MOOC?
Lesson 1: Introduction to traits and heredity
Trait variation and categorization, basic models of inheritance, and the connection via DNA. Check out the concept map for this lesson.
Lesson 2: Defining the genome
DNA structure, chromosomes, and genome organization. Check out the concept map for this lesson.
Lesson 3: How a genome works
Protein coding genes, transcription, translation, discerning the genetic code, and alleles. Check out the concept map for this lesson.
Lesson 4: Gene regulation
Non-coding DNA, regulatory regions of genes, and transcription factors. Check out the concept map for this lesson.
Lesson 5: Transmission of genes and traits
Family relationships and pedigrees, inheritance patterns, allele dominance, and chromosome dynamics.
Lesson 6: Origin of mutation/variation
Types of mutations, various causes of mutation, allelic frequency, and the spread of alleles in a population
Lesson 7: How to obtain and interpret genomic information
Personalized genetics: sample acquisition, DNA extraction and processing, and interpretation of results
Lesson 8: Simple genetic traits
Molecular causes of monogenic traits, loss-of-function vs. gain-of-function alleles, and dominance.
Lesson 9: Multifactorial traits
Polygenic traits, complex traits with an environmental effect, qualitative and quantitative measures, twin studies, relative risk, and genome-wide association studies (GWAs)
Lesson 10: Pharmacogenetics: genes and drugs
Pharmacokinetics and pharmacodynamics, alleles affecting drug metabolism, and personalized medicine
Lesson 11: Human ancestry and evolution
Identity by state (IBS), Identity by descent (IBD), relative finder, maternal and paternal lineages, neanderthal interbreeding, and human/chimp evolution
Lesson 12: The immortal genome
Personal decisions, moral quandaries, legal questions, and the future of genetics
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