Thanks all for the stimulating discussion and encouragement!
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-- We're hoping to use native Lacto (or maybe S. thermophillus) parts/DNA as much as possible. Native lacto promoters should be fine for the first pass, both from a scientific point of view and to make it easy for regulators/critics. No sense in making it harder on all of us.
Of the many anti-GMO concerns, one that is legitimate to me is the allergen issue of heterologous proteins. So we have to test allergenicity, just like for of any new food. (I don't know if computational prediction is sufficient; maybe to get the ball rolling, or as a necessary pre-screen). That will also cover any unintended side effects of the engineering (increased expression of something allergenic, change in post-translational mods of native proteins that may increase allergenicity, etc.) Low prob, but might as well check.
We're not trying to lead the pro-GMO charge explicitly here. We _are_ trying to be clear about exactly what we're doing without needlessly provoking anyone. I think releasing a good, safe engineered product is one of the best way to provide good press to the whole movement.
Best,
Rich
On Wed, Oct 9, 2013 at 7:28 AM, Mega [Andreas Stuermer] <masterstorm123@gmail.com> wrote:
Some good points were listed... haters keep hating, for sure.
But if you use romanticistic language, also people that were open-minded perheps get sceptical. If you allow conspiracy theories to grow.
It's a great product, and there will be people consuming it for sure!
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