Kanamycin and chloramphenicol are some of the few heat-resistant antibiotics. Indeed, kanamycin-resistance genes are used for selection of transformed cells in studies with Thermus spp. One of the few antibiotics suitable to work with thermophiles
El martes, 10 de diciembre de 2013 08:11:19 UTC+11, Nathan McCorkle escribió:
-- El martes, 10 de diciembre de 2013 08:11:19 UTC+11, Nathan McCorkle escribió:
On Fri, Dec 6, 2013 at 1:47 AM, Cuong Le <cuong...@gmail.com> wrote:
> I know this is late, but I was looking for thermal degradation data myself
> and after I found it I figured I would post it here for anyone else that
> stumbles on this thread:
>
> Heat stability of the antimicrobial activity of sixty-two antibacterial
> agents
> J. Antimicrob. Chemother. (1995) 35 (1): 149-154.
> doi: 10.1093/jac/35.1.149
Thanks for the great reference!
Here:
http://diyhpl.us/~nmz787/pdf/Journal_of_Antimicrobial_ Chemotherapy_1995_Traub_149- 154.pdf
So I'd think the one's that are heat-labile should be at the top of
the DIY usage list, so any discarded media wouldn't contain any active
antibiotics to aid selection for potential DNA-induced horizontal
transfer. Maybe labs should have some DNase on hand too, or maybe that
should be engineered in a organelle that will do some clean-up on cell
death (programmed or otherwise).
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