Re: [DIYbio] Biosecurity

Wanted to try and quantify how much DNA is being made. Found a report listing the market cap of oligonucleotide synthesis in 2017 at $1.47 Billion USD. Generously assuming a $0.01 / bp synthesis cost. That's ~147 billion base pairs, a good amount of DNA but nothing an organism cant produce (second source). Probably an amount of DNA you come into contact with over a short time period. Also, imo most of the market will be primers which will be inert. If you have better numbers I'd love to see them but this is just to benchmark what we are discussing.

As to your worry about laboratory contamination leading to novel and active sequences, I think you should design a simple experiment to test your hypothesis. This forum might even be a useful resource for an adversarial collaboration. 

If it means anything, I think you are directional correct but as was mentioned above, there is more friction to the creation of replicating DNA than it appears you believe.



On Tuesday, May 28, 2019 at 6:09:56 PM UTC-4, Matt Endrizzi wrote:
Yeah, that is where the conversation usually ends.  I don't mean to scare anyone.  I don't want to be right.

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