If it's a membrane protein (since it's a receptor, I'm guessing it is), it is extra tricky to recombantly express at high levels, and to crystallize it. To add to that, without access to a high powered X-ray source and nice detector, DIY crystallography would be a no go.
On the other hand, doing computational modeling of the receptor is definitely a realistic DIY project. You can use a service like Swiss Model (http://swissmodel.expasy.org/) to make some homology models of your animal receptors based upon the human receptor structure.
On Sun, Mar 6, 2016 at 7:59 PM Nathan McCorkle <nmz787@gmail.com> wrote:
I would read up on these keywords, and look for collaborators that you could get in with:On Sun, Mar 6, 2016 at 2:03 PM, Mega [Andreas Stuermer] <masterstorm123@gmail.com> wrote:Hi everybody,--I was wondering whether it is possible to characterize a specific receptor from an animal species.The human homologue of the receptor is known.So what would be needed is extract the receptor from the tissue, and analyze the structure. Is there a DIY way to do it? Is there anyone working on a similar project? How much would the equipment cost roughly?Would be very grateful for any keywords you might know!
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